The drug is supposed to be taken half an hour before physical intercourse and it lasts in the body for four hours approx. giving an erection time and physical pleasure of four hours continuous. Though the drug required appropriate sexual stimulation after which the process of erection initiates till a sustainable level of erection is achieved. The drug is targeted for impotence, however, many use it for recreational purposes to add extra libido.
The drug is available the dosages of 25, 50 and 100 milligram blue coloured tablets to be taken not more than once a day. Inappropriate for children under 18 years of age, over dosage of he drug would lead to circulatory collapse and fainting.
If you have prostate problem or take alpha blockers, the physician recommend the lowest dosage of 25mg per 48 hours. Men over 65 years of age are prescribed lowest dosage to secure health. Individuals with serious kidney or hepatic impairments are also restricted to 25mg dosage and no more since overdosing would lead to impaired drug metabolism. Alcoholism is considered a strict restriction for appropriate drug administration to be ensured. Men under 65 years of age and without any such disorders are first given 25mg dose after which it is gradually increased till satisfactory efficacy in penile erection is achieved.
Chemically, the drug is associated with protecting the smooth muscle relaxant cGMP in the penile vasculature by inhibiting the action of its degrading enzyme called as PDE5. This way, Viagra is often called as PDE5 inhibitor. The production of NO is necessary evil otherwise the drug would be rendered useless. This NO production by the vascular endothelial cells is stimulus mediated requiring arousal and sensual influence on the body, after which cGMP, produced by the action of NO on guanylate cyclase of penile vasculature, is prevented from degradation by the drug and impotence is relieved by causing rapid filling of penis with blood in the distended vasculature. In this way, Viagra promotes libido in men suffering from ED.
Headache, chest pain, nasal congestion and difficult breathing, dizziness, cyanotic vision and blurring, reduced hearing, heart burn and other stomach disorders, allergic reactions and priapism are some of the side effects of the drug. In case of appearance of any of these, immediately report to the doctor for prevention of further complications.
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